Ultrahigh spatiotemporal Resolution Optical Measurement and Lab-on-a-Chip Applications
讲座名称：
Ultrahigh spatiotemporal Resolution Optical Measurement and Lab-on-a-Chip Applications
讲座时间：
2016-01-06
讲座人：
王归仁
形式：
校区：
兴庆校区
实践学分：
讲座内容：
应徐峰教授邀请，美国南卡罗来纳大学王归仁副教授来我院学术交流，并为我院师生做学术报告，具体如下：
讲座题目：Ultrahigh spatiotemporal Resolution Optical Measurement and Lab-on-a-Chip Applications
讲座时间：2016年1月6日（周三）上午10：00
讲座地点：生命学院308报告厅
讲座人：王归仁
讲座摘要：As a multidisciplinary and new field, micro/nanofluidics based lab-on-a-chip is attracting interests of many scientists and engineers from various areas. In order to develop novel microfluidic device or understand physiology, pathology and pharmacology, some fundamental issues (physical, chemical and biological properties) in interfacial flows have to be addressed and measured with nanoscale resolution. However, current measuring techniques have mostly spatial resolution on the order of a few micrometers using micro- or nanoparticles as tracers, whose velocity in many cases is unfortunately different from that of fluids. Here we introduce a novel small and neutral molecules as the tracer, i.e. Laser Induced Fluorescence Photobleaching Anemometer (LIFPA), to measure flow velocity in micro- and nanochannels. We also developed a far field optical nanoscopy based on stimulated emission depletion (STED) with femto lasers. STED nanoscopy will be a powerful new tool in science and engineering. Integrated with STED, LIFPA has potential to measure interfacial flows, such as slip flow in biofluids with unprecedented high spatial (~ 70 nm) and temporal resolution (5 µs) resolution in micro/nanofluidics. We also use STED for nanofabrication of nanostructures to overcome diffraction limit in photolithography. Finally we introduce our microfliudic cell sorter based on dielectrophoresis for cancer cell separation.
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