2014诺贝尔奖得主西安交大校园行讲座(三)

讲座名称: 2014诺贝尔奖得主西安交大校园行讲座(三)
讲座时间 2014-09-18
讲座地点 科学馆101报告厅
讲座人 铃木章
讲座内容
2014诺贝尔奖得主西安交大校园行讲座(三)

 

讲座名称:Cross-Coupling Reactions of Organoboranes: An Easy Way for Carbon-Carbon Bonding
讲座时间:2014年9月18日下午4:00-5:00
讲座地点:科学馆101报告厅
讲座人:2010诺贝尔化学奖得主铃木章Akira Suzuki
讲座内容:
The palladium-catalyzed cross-coupling reaction between different types of organoboron compounds and various organic halides or triflates in the presence of base provides a powerful and general methodology for the formation of carbon-carbon bonds.   The (sp3)C-B compounds (alkylboron compounds) and (sp2)C-B compounds (such as aryl- and 1-alkenylboron derivatives) readily cross-couple with organic electrophiles to give coupled products selectively in high yields.   Recently, the (sp)C-B compounds (1-alkynylboron derivatives) have been also observed to react with organic electrophiles to produce expected cross-coupled products.  
Such coupling reactions offer several advantages:        
(1)  ready availability of reactants
(2)  mild reaction conditions
(3)  water stability
(4)  easy use of the reaction both in aqueous and heterogeneous conditions
(5)  toleration of a broad range of functional groups
(6)  highregio- and stereoselectivity of the reaction
(7)  insignificant effect of steric hindrance 
(8)  use of a small amount of catalysts
(9)  application in one-pot synthesis
(10) nontoxic reaction
(11) easy separation of inorganic boron compound
(12) green chemistry 
These coupling reactions have been actively utilized not only in academic laboratories but also in industrial processes including pharmaceutical and agrochemical industries, and liquid crystal and OELD production. 
In this lecture, the overview of the coupling reaction will be discussed to understand the whole.

 

讲座人介绍
讲座人简介:
铃木章,日本化学家,北海道大学荣誉教授,铃木反应的发现者。因在“有机合成中的钯催化交叉偶联反应”方面做出贡献,于2010年与理查德•赫克、根岸英一共同获得2010年诺贝尔化学奖。这一成果广泛应用于制药、电子工业和先进材料等领域。
铃木章发现卤代烃与有机硼化合物在钯催化下发生的偶联反应,现称为铃木反应。此外他也从事抗癌药、艾滋病治疗药物、液晶制造、有机合成化学与材料科学等领域的研究。
 

讲座视频 查看讲座视频

(转载文章,请注明出处: 西安交通大学学术资源平台 http://meeting.xjtu.edu.cn)

如果您有学术信息和动态,欢迎投稿,wuxuan@mail.xjtu.edu.cn。我们将在第一时间确认并收录