The Tumor Microenvironment and Metastasis
讲座名称：
The Tumor Microenvironment and Metastasis
讲座时间：
2012-11-19
讲座人：
Isaac P. Witz
形式：
校区：
兴庆校区
实践学分：
讲座内容：
应生命科学技术学院与前沿科学技术研究院转化医学研究中心主任陆五元教授邀请，以色列特拉维夫大学免疫学教授兼国际癌症微环境协会主席Isaac P. Witz和美国德克萨斯大学MD Anderson癌症研究中心教授Menashe Bar-Eli将于11月19日下午3点在主楼B303面向全校师生做学术报告。
学术报告时间：11月19日下午3:00
学术报告地点：主楼B303
学术报告人：
（一）Prof. Isaac P. Witz
Department of Cell Research and Immunology
Tel Aviv University, Tel Aviv, Israel
学术报告题目：The Tumor Microenvironment and Metastasis
学术报告摘要：A solid tumor is composed of tumor cells, resident and infiltrating non-tumor cells, and molecules present in proximity to these cells. This ecosystem can be collectively described as the tumor microenvironment. Both the tumor cells as well as the neighboring non-tumor cells take part in establishing the specific conditions existing in the microenvironmental milieu.
It is well established that the tumor microenvironment serves as an interaction ground between microenvironmental components and tumor cells. Each of the interactive partners is capable of regulating gene expression in all the other partners, thereby shaping their phenotype. As such, the tumor microenvironment operates primarily as an active “educational/inductive/selection” venue in which the tumor is directed into one of several molecular evolution pathways. In other words, by exerting regulatory functions and selective pressures, the tumor microenvironment determines and shapes the malignancy phenotype of cancer cells and as such drives tumor progression and metastasis.
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