Complex Neural Connectivity: Perspective from Cost-Efficiency Trade-off

讲座名称: Complex Neural Connectivity: Perspective from Cost-Efficiency Trade-off
讲座时间: 2018-08-05
讲座人: 周昌松
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校区: 兴庆校区
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讲座内容: 报告人:周昌松 教授 时间:2018年8月5日上午9.30-12.00 地点:航天航空学院教一楼第二会议室 报告题目:Complex Neural Connectivity: Perspective from Cost-Efficiency Trade-off We are interested in understanding neural systems as functional, complex dynamical networks. The brain is highly energy consuming, therefore is under strong evolution pressure to achieve cost-efficiency in both cortical connectivity and activity. In our recent works, we emphasized that the formation of the complex network architecture and dynamical activity of neural systems is subject to multiple structural and functional constraints. In the macaque brain connectome, we showed that network connectivity indeed displays a cost-efficiency trade-off, and up to 67% of the existing links can be recovered by the trade-off model. The model also reveals new organization feature of long distance-connectors (LDCs) in the system which are crucial for both functional segregation and integration. The perspective of cost-efficiency trade-off could provide a framework to better understand various salient features in neural connectivity and activity, and likely also suggest a novel angle to study the inherent vulnerability in brain networks which could be closely related to various neurodegenerative diseases and brain disorders.
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