Nano/Micro Fluidic Systems for Circulating Tumor Cells (CTCs) Rapid Detection and Diagnosis (奈微米生医流体系统应用于肿瘤循环细胞之筛检)

讲座名称: Nano/Micro Fluidic Systems for Circulating Tumor Cells (CTCs) Rapid Detection and Diagnosis (奈微米生医流体系统应用于肿瘤循环细胞之筛检)
讲座时间: 2016-10-20
讲座人: 曾繁根
形式:
校区: 兴庆校区
实践学分:
讲座内容: 应机械学院蒋庄德院士和韦学勇教授的邀请,台湾清华大学Fan-Keng Tseng教授来我校交流并作学术讲座。 报告题目:Nano/Micro Fluidic Systems for Circulating Tumor Cells (CTCs) Rapid Detection and Diagnosis (奈微米生医流体系统应用于肿瘤循环细胞之筛检) 报告地点:交大科技园西五楼A424 报告时间:10月20日上午9:30 报告简介:Despite the recent advancement of biotechnology and pharmaceutical research, cancers remain the leading cause of human mortality. It is vital to diagnose cancers at an early stage when treatment can dramatically improve prognosis. So far, low-cost and easy to operate devices, which allow efficient isolation and sensitive detection of circulating tumor cells (CTCs) for routine blood screening, remain lacking. This talk will introduce a novel micro fluidic platform which can isolate CTCs from the real blood sample in 30 minutes: this system includes a high throughput blood cell separation chip which can separate white blood cells with CTCs from red blood cells and platelets by inertial and suction actions; a nano structured surface which can allow higher retention rate of CTCs on the surface for sample enrichment by 100 folds from 1/107 up to 1/105 CTCs/WBCs.;and the enriched sample will go through a final cells self-assembly process into a densed monolayer on a cell assembly chip for in parallel inspection at high speed.  As a result, the CTCs can be identified in 30 minutes by the integration of these three chips altogether.  Isolated CTCs will still be in vital and can be further characterized and cultivated for the identification of cancer stem cells for prognosis.  
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